Therapeutic Hypothermia in Brain Trauma Injury: Controversies
نویسندگان
چکیده
منابع مشابه
Therapeutic Hypothermia in Traumatic Brain Injury
Traumatic brain injury (TBI) is a major source of death and severe disability worldwide. In the USA alone, this type of injury causes 290,000 hospital admissions, 51,000 deaths, and 80,000 permanently disabled survivors [1,2]. Intracranial hypertension develops commonly in acute brain injury related to trauma [3,4]. Raised Intracranial pressure (ICP) is an important predictor of mortality in pa...
متن کاملTherapeutic hypothermia in traumatic brain injury.
Traumatic brain injury is a leading cause of death by trauma in adults in the United States and a major contributor to permanent physical, emotional, and psychological disabilities. Therapeutic hypothermia, defined as cooling of the body to less than 36 degrees C, has been shown to decrease mortality and morbidity and improve long-term outcomes by protecting the brain from secondary brain injur...
متن کاملTherapeutic Hypothermia in Stroke and Traumatic Brain Injury
Therapeutic hypothermia (TH) is considered to improve survival with favorable neurological outcome in the case of global cerebral ischemia after cardiac arrest and perinatal asphyxia. The efficacy of hypothermia in acute ischemic stroke (AIS) and traumatic brain injury (TBI), however, is not well studied. Induction of TH typically requires a multimodal approach, including the use of both pharma...
متن کاملRevisiting therapeutic hypothermia for severe traumatic brain injury… again
Improved understanding of the molecular mechanisms of secondary brain injury has informed the optimum depth and duration of cooling and led to increased clinical interest in the therapeutic moderate hypothermia for severe traumatic brain injury over the past two decades. Although several large multi-center clinical trials have not found a treatment effect, multiple single-center trials have, an...
متن کاملTherapeutic Hypothermia for Brain Ischemia
Mild hypothermia is an established neuroprotectant in the laboratory, showing remarkable and consistent effects across multiple laboratories and models of brain injury. At the clinical level, mild hypothermia has shown benefits in patients who have experienced cardiac arrest and in some pediatric populations experiencing hypoxic brain insults. Its role, however, in stroke therapy has yet to be ...
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ژورنال
عنوان ژورنال: Romanian Neurosurgery
سال: 2014
ISSN: 2344-4959,1220-8841
DOI: 10.2478/romneu-2014-0035